Therapeutic areas
Comprehensive expertise across every domain
Multidisciplinary expertise across a broad range of therapeutic areas, supporting informed clinical and commercial decisions globally.
- 24Therapeutic areas
- 7Specialty clusters
- 6Evidence dimensions
Therapeutic area explorer
Seven specialty clusters. One evidence partner.
Select a cluster to see the areas it covers and the kind of evidence questions we help teams answer.
Oncology & Hematology
Evidence for complex, fast-moving treatment landscapes where outcomes, sequencing and value are closely scrutinised.
Areas covered
- Oncology
- Hematology
Typical evidence questions
- Survival, response and progression outcomes across lines of therapy
- Real-world treatment patterns and sequencing
- Health-state utilities by progression status
- Cost of illness and resource use across disease stages
Cardio-Respiratory & Metabolic
Long-term outcomes, chronic disease burden and value evidence for high-prevalence conditions.
Areas covered
- Cardiovascular
- Respiratory
- Endocrinology
- Nephrology
- Gastroenterology
Typical evidence questions
- Long-term cardiovascular, renal and respiratory outcomes
- Prevalence, comorbidity and disease burden
- Adherence and persistence in chronic therapy
- Cost-effectiveness and budget impact of chronic management
Neuroscience & Mental Health
Evidence that captures progression, function and the humanistic burden on patients and caregivers.
Areas covered
- Neurology
- Psychiatry & Mental Health
- Geriatrics
Typical evidence questions
- Disease progression and natural history
- Patient-reported outcomes and caregiver burden
- Quality-of-life and utility values
- Treatment patterns and unmet needs
Immunology, Infection & Vaccines
From prevention to long-term disease control - efficacy, safety, epidemiology and programme value.
Areas covered
- Immunology & Autoimmune
- Infectious Diseases
- Vaccines
- Dermatology
Typical evidence questions
- Efficacy, safety and immunogenicity evidence
- Incidence, prevalence and epidemiology
- Economic evaluations of prevention programmes
- Flare, remission and long-term disease control
Rare Disease & Special Populations
Careful evidence synthesis where data are sparse, populations are small and every study counts.
Areas covered
- Rare Diseases
- Pediatrics
- Women's Health
Typical evidence questions
- Natural history in small, heterogeneous populations
- Evidence in pediatric and other special populations
- Burden of illness and unmet needs
- Scoping and gap assessments where evidence is sparse
Specialty Care
Function, patient experience and care-pathway evidence across specialist settings.
Areas covered
- Musculoskeletal
- Ophthalmology
- ENT
- Dental & Oral Health
Typical evidence questions
- Functional and patient-reported outcomes
- Treatment patterns across care settings
- Healthcare resource utilization and costs
- Comparative effectiveness of interventions
Cross-cutting & Innovation
Evidence for the next generation of care - precision approaches, digital solutions and safety science.
Areas covered
- Precision Medicine
- Pharmacovigilance
- Digital Therapeutics & AI
Typical evidence questions
- Safety evidence and pharmacovigilance literature
- Biomarker-defined and precision medicine populations
- Evidence for digital therapeutics and AI-enabled care
- Landscape and competitive evidence reviews
Find your therapeutic area
The periodic table of our expertise
Twenty-four therapeutic areas, seven specialty clusters. Hover or tap any element to learn more - or search and filter to find yours.
Oncology
Evidence for complex, fast-moving treatment landscapes where outcomes, sequencing and value are closely scrutinised.
Don’t see your therapeutic area? Tell us about your project and we will discuss how we can help.
Talk to usEvery area, every evidence dimension
The evidence we synthesize, whatever your therapeutic area
Our reviews help teams understand treatment outcomes, disease burden, healthcare resource use, quality of life and published economic evidence.
Clinical evidence
Efficacy, effectiveness and safety outcomes, plus subgroup and special-population evidence where available.
Economic evidence
Cost of illness, healthcare resource utilization, direct and indirect costs, and published CEA, CUA and BIA.
Humanistic evidence
Health-related quality of life, patient-reported outcomes and health-state utilities.
Epidemiology
Disease incidence and prevalence, disease burden and unmet needs reported in published studies.
Treatment patterns
Evidence on how interventions are used across defined populations and care settings.
Natural history
Evidence on disease prognosis and progression over time.
Evidence across the lifecycle
From early research to post-marketing
Whatever your therapeutic area, our team supports evidence generation across the product lifecycle.
- Stage 1
Early research
Scoping reviews, evidence gap assessments and landscape analysis.
- Stage 2
Clinical development
Systematic literature reviews, epidemiology and natural history evidence.
- Stage 3
Regulatory
Regulatory, publication and value dossier writing.
- Stage 4
Market access & HTA
Health economic models and value demonstration.
- Stage 5
Post-marketing
Real-world evidence and outcomes studies, SLR updates and publications.
Working in a specific indication? Share your question, population, interventions, outcomes and deadline - we will assess scope, feasibility and the right review approach.
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